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Ecstasy drug a potential PTSD treatment

Ammo

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http://www.torontosun.com/news/canada/2010/08/04/14923656.html

OTTAWA — Canada's military would use the illicit dance-floor drug Ecstasy to treat soldiers with post-traumatic stress disorder if it's proven safe and effective, says a top DND doctor.

Lt. Col. Rakesh Jetly, a psychiatrist and senior health adviser for the Canadian Forces, said the department of national defence (DND) is committed to evidence-based care, and would embrace any treatment that has undergone rigorous scientific research to help relieve suffering of battle-scarred troops.

"If you replaced Ecstasy with substance X - whether it was an absolutely approved legal drug, a mainstream medication, my answer would be the same. The fact that it's Ecstasy means nothing to us," Jetly told QMI Agency. "If there's any substance, any drug that has the research, the randomized controlled studies, the publications to prove its efficacy, we would entertain adding it as an approved treatment."

A new study published in the Journal of Psychopharmacology shows a small clinical trial found 80% of chronic patients treated with psychotherapy and MDMA - called Ecstasy on the street — no longer showed signs of t-traumatic stress disorder if (PTSD) and had no serious side effects. Three patients once so debilitated by the disorder they couldn't work were able to return to their jobs after treatment.

MDMA was used by psychiatrists and psychotherapists to aide treatment before it was outlawed in the 1970s and 1980s.

Jetly said because all treatments endure broad-based, tough scientific scrutiny and robust risk assessments support before they are ever approved by Health Canada, he is not bothered that a potential remedy stems from a street drug.

"If there's merit and the benefits outweigh the risks of adverse effects, then everything is fair game to consider, if there's evidence to prove its efficacy," he said. "From our point of view, we're in the business of stopping suffering and if something is shown to do it then we would certainly give it serious consideration."

But Commodore Hans Jung, the CF Surgeon General, warned studies on Ecstasy are still in the very early stage and that it would take many years of tests and research before it might be deemed ready for regulatory approval. Any soldiers suffering from PTSD should seek professional care and should never self-medicate or treat themselves with any drug that has not been proven to be safe, he said.

The Multidisciplinary Association for Psychedelic Studies, which sponsored the Ecstasy pilot with subjects traumatized by war, crime and abuse, is conducting a second focused trial with veterans from Afghanistan, Iraq and Vietnam. Other clinical trials are planned for Canada, Switzerland and Jordan.

MAPS spokesman Randolph Hencken said the Health Canada-approved Vancouver project was delayed due to "bureaucratic hurdles" moving the Ecstasy across the border but is now expected to launch in the next few months.

"We believe it will be a good option in that it actually treats the causes as opposed to masking the symptoms," he told QMI Agency, noting the goal of approval of the drug as a prescribed medication is likely still years away. "People who have PTSD and have been afraid to face the trauma and overcome it, when they use MDMA-assisted psychotherapy they are able to comfortably discuss the trauma, face the issues and overcome them."
 
While I can't be certain as I'm not a health care professional, the medicine which would be used on our troops would not be the same type of drug an individual 'could' buy on the streets. Not only would it be of higher and better quality, it would likely be more advance and more modified to suit the needs of an individual who may need it.

After being an eye witness to the continuing degeneration of P.T.S.D on a healthy individual, I can only state that this is a much needed and much welcome development. Although I can see how individuals may be reluctant to try the new medicine if it has not been thoroughly studied and if it continues to be given the ecstasy moniker.
 
At least 10 years away before Health Canada will approve prescription.
 
That's really good news; glad that they've finally gotten to this stage. Doesn't make sense that we'll keep people stupified on some drugs to 'manage' the symptoms while not using others as part of an actual treatment due to social stigmas.
 
You know, we have a research center for CBRN which are illigal in warfare, how do we not have a research center to see if known drugs have practical uses?
 
You know, we have a research center for CBRN which are illigal in warfare, how do we not have a research center to see if known drugs have practical uses?
I watched a documentary about a year or two ago about researchers using MDMA to treat PTSD.

I believe the woman it focused on (there was a man as well, and they did not know each other) was a sexual assault victim.

I remember her saying she had made more progress with small, controlled doses of MDMA under the direction of the researchers, combined with meditation and some lifestyle changes, than she ever had with big pharma drugs.


The west needs to re-evaluate it’s approach when it comes to certain drugs.

Researching something that could potentially be more helpful with less side effects than drugs produced by big pharmaceutical companies isn’t ‘dangerous’ as some have labelled the idea.

Charging ahead based on stigmas and not being open to change is far more dangerous, I would think.


Happy Monday folks 😊👍🏻
 
You know, we have a research center for CBRN which are illigal in warfare, how do we not have a research center to see if known drugs have practical uses?
It takes a lot of effort to get proper approval, but this particular treatment of PTSD using MDMA has taken decades to get enough small studies done to get approval for a bigger study. I think it requires some people to really push it, the article below talks a bit about how this all came about as part of the therapy sessions;

MDMA Shows New Promise for Trauma, but the Drug Alone Is Not a Cure

The other big one is psilocybin, which seems to have a lot of potential for treating depression.
 
My wife's niece just received her doctorate from UC-Berkley researching how to remove the 'debilitating' effects of psychedelic drugs so that what's left has a safe medicinal value (most of what she described was over my head). Apparently there is incredible potential. I just thought the venue was serendipitous.
 
I recently listened to a podcast where a Dr. was discussing the use of MDMA for treating PTSD. It's quite involved, with a team of professionals working with the patient, but they report very high success rates.

It's good to see that medicine is looking into alternatives to the current practices, particularly in the field of mental health.
 
My wife's niece just received her doctorate from UC-Berkley researching how to remove the 'debilitating' effects of psychedelic drugs so that what's left has a safe medicinal value (most of what she described was over my head). Apparently there is incredible potential. I just thought the venue was serendipitous.
Anyone remember why it was banned in the first place?
Hint, it involved the use of Canadian patients - and the CIA.
 
I'm always a cynic when it comes to experimenting with drugs.
Often the $ is looking for Advancements in performance - and not as concerned with treatment.

I am curious who is funding a lot of the studies - as relief of Veteran PTSD seems to be a small peanuts reward, as opposed to what else might be the primary focus of research -- again see MK Ultra.
 
I'm always a cynic when it comes to experimenting with drugs.
Often the $ is looking for Advancements in performance - and not as concerned with treatment.

I am curious who is funding a lot of the studies - as relief of Veteran PTSD seems to be a small peanuts reward, as opposed to what else might be the primary focus of research -- again see MK Ultra.

Bud you're right on so many levels.
 
You know, we have a research center for CBRN which are illigal in warfare, how do we not have a research center to see if known drugs have practical uses?

Such research happens all the time. Search of: mdma - List Results - ClinicalTrials.gov or Search of: PTSD | Canada - List Results - ClinicalTrials.gov

However, why doesn't the CAF/DND have such a "research centre"? Because the CAF is actually small potatoes, in terms of number of patients (potential patients) and the number of clinicians available to do dedicated research, though I'm sure some have been involved in clinical trials.

And though we have a "CBRN research centre" (I assume you're referring to Suffield), its focus is on defence and mitigation of NBC threats (oops sorry, my abbreviation is as dated as my involvement in trials there) and not with weapons development. And while I would not suggest that some chemical or biological substances that could be used as weapon precursors are not kept there, their use would be limited and does not extend to being tested on humans.
 
Remember also that often a drug is found not to address the condition it was thought it would, but then gets researched further based on side effects. Neither Minoxidyl or Viagra were originally created to promote hair growth or erections.
 
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